2-Bromo-5-methoxybenzoic acid → 2-(2,5-Dimethoxybenzoyl)-5-methoxybenzoic acid

HRID 30020노트

반응식

HRID 30020 반응식
Br[C:2]1[CH:10]=[CH:9][C:8]([O:11][CH3:12])=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].C([Li])CCC.[CH3:18][O:19][C:20]1[CH:31]=[CH:30][C:29]([O:32][CH3:33])=[CH:28][C:21]=1[C:22](N(OC)C)=[O:23]>>[CH3:18][O:19][C:20]1[CH:31]=[CH:30][C:29]([O:32][CH3:33])=[CH:28][C:21]=1[C:22]([C:2]1[CH:10]=[CH:9][C:8]([O:11][CH3:12])=[CH:7][C:3]=1[C:4]([OH:6])=[O:5])=[O:23]

참가 물질

4

반응물 3

HCID 899062-Bromo-5-methoxybenzoic acidHCID 18931310N,2,5-trimethoxy-N-methylbenzamideHCID 178418339Butyllithium

생성물 1

HCID 692122442-(2,5-Dimethoxybenzoyl)-5-methoxybenzoic acid

실험 절차

This compound is synthesized according to the method described in 3.2. by reacting 2-bromo-5-methoxybenzoic acid pretreated with n-butyllithium with 2,5-dimethoxy-N-methoxy-N-methylbenzamide. It is crystallized from diisopropyl ether.

후처리

  1. customThis compound is synthesized
  2. customIt is crystallized from diisopropyl ether

출처 및 근거

ORD 기록
ord-dd638509591b49f5843084af3c32ff33
출처 데이터셋
uspto-grants-2008_09
특허 번호
US07423030B2

반응 노트

불러오는 중…