Imidazole → Tert-butyl 2-[[1-amino-3-[4-[3-[2-[tert-butyl(dimethyl)silyl]oxyethyl]-2-oxo-1,3-benzothiazol-6-yl]phenyl]-1-oxopropan-2-yl]carbamoyl]piperidine-1-carboxylate

HRID 300470

반응식

[C:41]([CH3:42])([CH3:43])([CH3:44])[Si:45]([CH3:46])([CH3:47])[Cl:48].[NH2:1][C:2]([CH:3]([CH2:4][c:5]1[cH:6][cH:7][c:8](-[c:11]2[cH:12][c:13]3[c:14]([n:15]([CH2:19][CH2:20][OH:21])[c:16](=[O:18])[s:17]3)[cH:22][cH:23]2)[cH:9][cH:10]1)[NH:24][C:25](=[O:26])[CH:27]1[N:28]([C:33](=[O:34])[O:35][C:36]([CH3:37])([CH3:38])[CH3:39])[CH2:29][CH2:30][CH2:31][CH2:32]1)=[O:40].[O:55]=[CH:56][N:57]([CH3:58])[CH3:59].[OH2:54].[nH:49]1[cH:50][cH:51][n:52][cH:53]1>>[NH2:1][C:2]([CH:3]([CH2:4][c:5]1[cH:6][cH:7][c:8](-[c:11]2[cH:12][c:13]3[c:14]([n:15]([CH2:19][CH2:20][O:21][Si:45]([C:41]([CH3:42])([CH3:43])[CH3:44])([CH3:46])[CH3:47])[c:16](=[O:18])[s:17]3)[cH:22][cH:23]2)[cH:9][cH:10]1)[NH:24][C:25](=[O:26])[CH:27]1[N:28]([C:33](=[O:34])[O:35][C:36]([CH3:37])([CH3:38])[CH3:39])[CH2:29][CH2:30][CH2:31][CH2:32]1)=[O:40]