(5-Fluoropyridin-3-yl)boronic acid → 6-(4-Fluorophenyl)-3-[1-[4-(5-fluoro-3-pyridinyl)phenyl]ethyl]-6-(3-hydroxypropyl)-1,3-oxazinan-2-one

HRID 300696

반응식

HRID 300696 반응식
[Br:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([CH3:9])[N:10]2[C:11](=[O:27])[O:12][C:13]([CH2:16][CH2:17][CH2:18][OH:19])([c:20]3[cH:21][cH:22][c:23]([F:26])[cH:24][cH:25]3)[CH2:14][CH2:15]2)[cH:6][cH:7]1.[F:28][c:29]1[cH:30][c:31]([B:35]([OH:36])[OH:37])[cH:32][n:33][cH:34]1>>[c:2]1(-[c:31]2[cH:30][c:29]([F:28])[cH:34][n:33][cH:32]2)[cH:3][cH:4][c:5]([CH:8]([CH3:9])[N:10]2[C:11](=[O:27])[O:12][C:13]([CH2:16][CH2:17][CH2:18][OH:19])([c:20]3[cH:21][cH:22][c:23]([F:26])[cH:24][cH:25]3)[CH2:14][CH2:15]2)[cH:6][cH:7]1

참가 물질

3

반응물 2

HCID 44717403(5-Fluoropyridin-3-yl)boronic acidHCID 907107973-[1-(4-Bromophenyl)ethyl]-6-(4-fluorophenyl)-6-(3-hydroxypropyl)-1,3-oxazinan-2-one

생성물 1

HCID 914264226-(4-Fluorophenyl)-3-[1-[4-(5-fluoro-3-pyridinyl)phenyl]ethyl]-6-(3-hydroxypropyl)-1,3-oxazinan-2-one

출처 및 근거

ORD 기록
ord-c773f524179345efae0985e8d708acfd
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

연결된 노트

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