Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 30085생성일: 2026년 10월 24일
Diphenyl N-Cyanocarbonimidate → Phenyl N-cyano-N'-(2-{[4-(2,4-difluorophenyl)-8-(2-fluorophenyl)-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl]amino}ethyl)imidocarbamate
https://huagongshe.com/ko/reaction/30085
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Diphenyl N-Cyanocarbonimidate | HCID 688090 | — |
| 반응물 | 2-[(2-Aminoethyl)amino]-4-(2,4-difluorophenyl)-8-(2-fluorophenyl)pyrido[2,3-d]pyrimidin-7(8H)-one | HCID 59789333 | — |
| 용매 | Isopropanol | HCID 3776 | — |
| 생성물 | Phenyl N-cyano-N'-(2-{[4-(2,4-difluorophenyl)-8-(2-fluorophenyl)-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl]amino}ethyl)imidocarbamate | HCID 59789332 | — |
반응 단계
To a solution of 2-[(2-aminoethyl)amino]-4-(2,4-difluorophenyl)-8-(2-fluorophenyl)pyrido[2,3-d]pyrimidin-7(8H)-one (28 mg, 0.070 mmol) in isopropanol (2 mL) was added diphenyl cyanocarbonimidate (17 mg, 0.070 mmol). The mixture was stirred for about 30 min at about 20° C. LC/MS showed a new peak corresponding to the desired product and no starting material in the solution. LC-MS m/z 556 (M+H)+, 3.24 min (ret time).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 특허 번호 | US07423042B2 |
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| 출처 데이터셋 | uspto-grants-2008_09 |
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| ORD ID | ord-83e404ccb1e94720998b7aad81cd5039 |
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| 출처 메모 | uspto-grants-2008_09 |
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