반응식
[NH2:1][C:2]1[C:7]([C:8]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=2[F:16])=[O:9])=[CH:6][CH:5]=[C:4](Cl)[N:3]=1.[CH2:18]([O:20][C:21]([N:23]1[CH2:28][CH2:27][CH:26]([NH2:29])[CH2:25][CH2:24]1)=[O:22])[CH3:19]>>[CH2:18]([O:20][C:21]([N:23]1[CH2:24][CH2:25][CH:26]([NH:29][C:4]2[CH:5]=[CH:6][C:7]([C:8](=[O:9])[C:10]3[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=3[F:16])=[C:2]([NH2:1])[N:3]=2)[CH2:27][CH2:28]1)=[O:22])[CH3:19]참가 물질
3
실험 절차
The title compound was prepared from (2-Amino-6-chloro-pyridin-3-yl)-(2-fluoro-phenyl)-methanone (Example 7) and ethyl-4-amino-1-piperidine carboxylate (Aldrich) using the procedure described in Step B. Example 6. HRMS, observed: 386.1762, calcd for M+: 386.1754.
출처 및 근거
- ORD 기록
- ord-0b0a6e779a6f49c4ab9303d399238a7b
- 출처 데이터셋
- uspto-grants-2008_09
- 특허 번호
- US07423051B2
연결된 노트
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