Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Bromo-1-(4-fluorophenyl)ethan-1-one → (RS)-2-[2-(4-Fluoro-phenyl)-2-oxo-ethoxycarbonylmethyl]-piperidine-1-carboxylic tert butyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Bromo-1-(4-fluorophenyl)ethan-1-one | HCID 96749 | — |
| 반응물 | 1-Boc-2-Piperidineacetic Acid | HCID 5058536 | — |
| 생성물 | (RS)-2-[2-(4-Fluoro-phenyl)-2-oxo-ethoxycarbonylmethyl]-piperidine-1-carboxylic tert butyl ester | HCID 86629009 | 96.9% |
반응 단계
The title compound (3.83 g) was prepared from (RS)-2-carboxymethyl-piperidine-1-carboxylic acid tert butyl ester (2.54 g) and 2-bromo-4′-fluoroacetophenone (2.26 g) according to the method of description 36.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07423052B2 |
| 출처 데이터셋 | uspto-grants-2008_09 |
| ORD ID | ord-bfa1eb39978b4e89b76325180d974536 |
| 출처 메모 | uspto-grants-2008_09 |