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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 30181생성일: 2026년 10월 25일

2-Bromo-3'-chloroacetophenone → (RS)-2-[2-(3-Chloro-phenyl)-2-oxo-ethoxycarbonylmethyl]-piperidine-1-carboxylic tert butyl ester

https://huagongshe.com/reaction/30181

반응식

참여 물질

역할이름HCID투입량
반응물2-Bromo-3'-chloroacetophenoneHCID 38738—
반응물1-Boc-2-Piperidineacetic AcidHCID 5058536—
생성물(RS)-2-[2-(3-Chloro-phenyl)-2-oxo-ethoxycarbonylmethyl]-piperidine-1-carboxylic tert butyl esterHCID 8662901181.4%

반응 단계

The title compound (2.65 g) was prepared from (RS)-2-carboxymethyl-piperidine-1-carboxylic acid tert butyl ester (2.0 g) and 2-bromo-3′-chloroacetophenone (1.92 g) according to the method of description 36.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07423052B2
출처 데이터셋uspto-grants-2008_09
ORD IDord-c95c2991bde54740a6af9825fb19498d
출처 메모uspto-grants-2008_09