Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-(2-Bromoacetyl)benzonitrile → (RS)-2-[2-(3-Cyano-phenyl)-2-oxo-ethoxycarbonylmethyl]-piperidine-1-carboxylic tert butyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-(2-Bromoacetyl)benzonitrile | HCID 2735867 | — |
| 반응물 | 1-Boc-2-Piperidineacetic Acid | HCID 5058536 | — |
| 생성물 | (RS)-2-[2-(3-Cyano-phenyl)-2-oxo-ethoxycarbonylmethyl]-piperidine-1-carboxylic tert butyl ester | HCID 86629012 | 82.7% |
반응 단계
The title compound (1.51 g) was prepared from (RS)-2-carboxymethyl-piperidine-1-carboxylic acid tert butyl ester (1.15 g) and 2-bromo-3′-cyanoacetophenone (1.06 g) according to the method of description 36.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07423052B2 |
| 출처 데이터셋 | uspto-grants-2008_09 |
| ORD ID | ord-6dcbf1f49ea5451f9f935ed91bf27ad3 |
| 출처 메모 | uspto-grants-2008_09 |