Dimethylformamide → [4-(1-Chloropyrido[3,4-d]pyridazin-4-yl)-3-methylpiperazin-1-yl]-(4,4-difluorocyclohexyl)methanone

HRID 302219

반응식

[CH3:27][CH2:28][N:29]([CH2:30][CH3:31])[CH2:32][CH3:33].[Cl:34][c:35]1[c:36]2[c:37]([c:38]([N:41]3[CH:42]([CH3:47])[CH2:43][NH:44][CH2:45][CH2:46]3)[n:39][n:40]1)[cH:48][n:49][cH:50][cH:51]2.[F:1][C:2]1([F:11])[CH2:3][CH2:4][CH:5]([C:8](=[O:9])[OH:10])[CH2:6][CH2:7]1.[O:12]=[C:13]1[N:14]([P:15]([Cl:16])([N:17]2[CH2:18][CH2:19][O:20][C:21]2=[O:22])=[O:23])[CH2:24][CH2:25][O:26]1.[O:52]=[CH:53][N:54]([CH3:55])[CH3:56]>>[F:1][C:2]1([F:11])[CH2:3][CH2:4][CH:5]([C:8](=[O:10])[N:44]2[CH2:43][CH:42]([CH3:47])[N:41]([c:38]3[c:37]4[c:36]([c:35]([Cl:34])[n:40][n:39]3)[cH:51][cH:50][n:49][cH:48]4)[CH2:46][CH2:45]2)[CH2:6][CH2:7]1