1-(4-Nitrophenyl)ethanamine → 5-[1-(4-Nitro-phenyl)-ethylcarbamoyl]-thiophene-2-carboxylic acid methyl ester

반응식

[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([CH:10]([NH2:12])[CH3:11])=[CH:6][CH:5]=1)([O-:3])=[O:2].[CH3:13][O:14][C:15]([C:17]1[S:18][C:19]([C:22](O)=[O:23])=[CH:20][CH:21]=1)=[O:16]>>[CH3:13][O:14][C:15]([C:17]1[S:18][C:19]([C:22](=[O:23])[NH:12][CH:10]([C:7]2[CH:6]=[CH:5][C:4]([N+:1]([O-:3])=[O:2])=[CH:9][CH:8]=2)[CH3:11])=[CH:20][CH:21]=1)=[O:16]

참가 물질

반응물 2

HCID 5919951-(4-Nitrophenyl)ethanamine

HCID 8183525-(Methoxycarbonyl)thiophene-2-carboxylic acid

생성물 1

HCID 691350675-[1-(4-Nitro-phenyl)-ethylcarbamoyl]-thiophene-2-carboxylic acid methyl ester

실험 절차

The title compound was prepared in an analogous manner to that described in example 1, step 3 from 1-(4-nitro-phenyl)-ethylamine and thiophene-2,5-dicarboxylic acid monomethyl ester.

출처 및 근거

ORD 기록: ord-05f67a3f27674791aee08b5008da6f65
출처 데이터셋: uspto-grants-2008_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07423060B2

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