5,5-Dimethyloxazolin-2-one → 3-{4-[4-(5-Cyclopropylpyridin-2-yl)piperazine-1-carbonyl]-3-fluorophenyl}-5,5-dimethyloxazolidin-2-one

반응식

[Br:1][c:2]1[cH:3][c:4]([F:25])[c:5]([C:8](=[O:9])[N:10]2[CH2:11][CH2:12][N:13]([c:16]3[n:17][cH:18][c:19]([CH:22]4[CH2:23][CH2:24]4)[cH:20][cH:21]3)[CH2:14][CH2:15]2)[cH:6][cH:7]1.[CH3:26][C:27]1([CH3:33])[CH:28]=[N:29][C:30](=[O:32])[O:31]1>>[c:2]1([N:29]2[CH2:28][C:27]([CH3:26])([CH3:33])[O:31][C:30]2=[O:32])[cH:3][c:4]([F:25])[c:5]([C:8](=[O:9])[N:10]2[CH2:11][CH2:12][N:13]([c:16]3[n:17][cH:18][c:19]([CH:22]4[CH2:23][CH2:24]4)[cH:20][cH:21]3)[CH2:14][CH2:15]2)[cH:6][cH:7]1

참가 물질

반응물 2

HCID 214647825,5-Dimethyloxazolin-2-one

HCID 58484657(4-Bromo-2-fluorophenyl)[4-(5-cyclopropylpyridin-2-yl)piperazin-1-yl]methanone

생성물 1

HCID 584846503-{4-[4-(5-Cyclopropylpyridin-2-yl)piperazine-1-carbonyl]-3-fluorophenyl}-5,5-dimethyloxazolidin-2-one

출처 및 근거

ORD 기록: ord-2a2ee5093648442d88b2edf616798b31
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

반응 노트

불러오는 중…