Dichloromethane → 2-{[6-(4-Fluoro-phenyl)-5-piperidin-1-yl-pyrazine-2-carbonyl]-amino}-2-methyl-propionic acid methyl ester

반응식

[CH3:29][O:30][C:31]([C:32]([CH3:33])([CH3:34])[NH2:35])=[O:36].[Cl:23][C:24]([C:25]([Cl:26])=[O:27])=[O:28].[Cl:37][CH2:38][Cl:39].[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9]([N:17]3[CH2:18][CH2:19][CH2:20][CH2:21][CH2:22]3)[n:10][cH:11][c:12]([C:14](=[O:15])[OH:16])[n:13]2)[cH:6][cH:7]1>>[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9]([N:17]3[CH2:18][CH2:19][CH2:20][CH2:21][CH2:22]3)[n:10][cH:11][c:12]([C:14](=[O:15])[NH:35][C:32]([C:31]([O:30][CH3:29])=[O:36])([CH3:33])[CH3:34])[n:13]2)[cH:6][cH:7]1