5-Bromo-2-hydroxypyridine → 4-[{2-[(5-Bromo-2-pyridinyl)oxy]ethyl}(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrile

반응식

[Br:22][c:23]1[cH:24][cH:25][c:26](=[O:29])[nH:27][cH:28]1.[OH:1][CH2:2][CH2:3][N:4]([c:5]1[cH:6][c:7]([C:13]([F:14])([F:15])[F:16])[c:8]([C:9]#[N:10])[cH:11][cH:12]1)[CH2:17][C:18]([F:19])([F:20])[F:21]>>[O:1]([CH2:2][CH2:3][N:4]([c:5]1[cH:6][c:7]([C:13]([F:14])([F:15])[F:16])[c:8]([C:9]#[N:10])[cH:11][cH:12]1)[CH2:17][C:18]([F:19])([F:20])[F:21])[c:26]1[cH:25][cH:24][c:23]([Br:22])[cH:28][n:27]1

참가 물질

반응물 2

HCID 5995285-Bromo-2-hydroxypyridine

HCID 866237314-[(2-Hydroxyethyl)(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrile

생성물 1

HCID 115689644-[{2-[(5-Bromo-2-pyridinyl)oxy]ethyl}(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrile

출처 및 근거

ORD 기록: ord-6c7b991aad684da3b91b981692ff3b5b
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

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