Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Carbonate → 3-(N,N-diethylaminopropoxy)butyranilide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | Butyranilide, 3'-hydroxy- | HCID 30688 | — |
| 반응물 | Methanesulfonate | HCID 85257 | — |
| 반응물 | Diethylamino-propanol | HCID 5256659 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 3-(N,N-diethylaminopropoxy)butyranilide | HCID 68428240 | 88.9% |
반응 단계
The mesylate of N,N-diethylaminopropanol (6 mmol), prepared as described in Example 18 above, was mixed with 3-butyramidophenol (5.0 mmol), and K2CO3 (10 mmol) in anhydrous DMF (10 mL) and the reaction is performed following general procedure B. The crude product is purified using silica gel column chromatography 5% MeOH/DCM as eluent to yield 3-(N,N-diethylaminopropoxy)butyranilide (1.3 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07423177B2 |
| 출처 데이터셋 | uspto-grants-2008_09 |
| ORD ID | ord-67fb278fb8d946049d25207848a9308e |
| 출처 메모 | uspto-grants-2008_09 |