Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl iodide → HCID 11359854, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl iodide | HCID 6328 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | N-[(Phenylmethoxy)carbonyl]-L-tyrosine methyl ester | HCID 7010613 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | HCID 11359854 | HCID 11359854 | — |
반응 단계
32.94 g (100 mmol) of N-benzyloxycarbonyl-tyrosine methyl ester is mixed in 200 ml of DMF with 27.64 g (200 mmol) of ground potassium carbonate. 15.6 g (110 mmol) of iodomethane is instilled in this suspension and stirred overnight at room temperature. The solution is concentrated by evaporation, dispersed between ethyl acetate and water, and the organic phase is mixed with hexane after drying (Na2SO4). The title compound crystallizes out.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05733522 |
| 출처 데이터셋 | uspto-grants-1998_03 |
| ORD ID | ord-dba6f3dde0664944932faac3af102356 |
| 출처 메모 | uspto-grants-1998_03 |