Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Bromo-2-iodobenzene → 2'-Bromo-4-(2-dimethylamino-ethoxy)-biphenyl-3-carbaldehyde
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Bromo-2-iodobenzene | HCID 11415 | — |
| 반응물 | 4-(2-Dimethylamino-ethoxy)-3-formyl-benzeneboronic acid | HCID 85888855 | — |
| 생성물 | 2'-Bromo-4-(2-dimethylamino-ethoxy)-biphenyl-3-carbaldehyde | HCID 86601007 | 68% |
반응 단계
General procedure G, using 4-(2-dimethylamino-ethoxy)-3-formyl-benzeneboronic acid and 1-bromo-2-iodo-benzene gave the title product as yellow oil in 68% yield. 1H-NMR (CDCl3) δ 10.51 (s, 1H), 7.90 (d, 1H), 7.70-7.65 (m, 2H), 7.41-7.20 (m, 3H), 7.09 (d, 1H), 4.40 (t, 2H), 3.04 (bs, 2H), 2.56 (s, 6H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07423181B2 |
| 출처 데이터셋 | uspto-grants-2008_09 |
| ORD ID | ord-808575f3ad864d1ca959865a121f6924 |
| 출처 메모 | uspto-grants-2008_09 |