Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Nitrobenzaldehyde → 5-(4-Nitrobenzylidene)-1,3-thiazolidine-2,4-dione
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Nitrobenzaldehyde | HCID 541 | — |
| 반응물 | Thiazolidinedione | HCID 5437 | — |
| 반응물 | Piperidine | HCID 8082 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 5-(4-Nitrobenzylidene)-1,3-thiazolidine-2,4-dione | HCID 2768264 | 59.2% |
반응 단계
A mixture of 4-nitrobenzaldehyde (15.1 g), 1,3-thiazolidine-2,4-dione (11.70 g), piperidine (1.70 g) and ethanol (300 mL) was heated under reflux for 24 hrs. The reaction mixture was concentrated. The obtained residue was washed with ethanol to give 5-(4-nitrobenzylidene)-1,3-thiazolidine-2,4-dione as yellow crystals (14.8 g, yield 59%). Recrystallization thereof from acetone-hexane gave pale-yellow prism crystals. melting point: 272-273° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07423159B2 |
| 출처 데이터셋 | uspto-grants-2008_09 |
| ORD ID | ord-02854ddf1583494d8386c11c20c29345 |
| 출처 메모 | uspto-grants-2008_09 |