2-(4-Fluorophenyl)propionic acid → N-[(3RS,4SR)-1-(1-cyclopropylmethyl-piperidine-4-carbonyl)-4-(3,4-dichloro-phenyl)-pyrrolidin-3-yl]-2-(4-fluoro-phenyl)-N-methyl-propionamide

HRID 306932

반응식

HRID 306932 반응식
[CH:1]1([CH2:4][N:5]2[CH2:6][CH2:7][CH:8]([C:11](=[O:12])[N:13]3[CH2:14][CH:15]([c:20]4[cH:21][c:22]([Cl:27])[c:23]([Cl:26])[cH:24][cH:25]4)[CH:16]([NH:18][CH3:19])[CH2:17]3)[CH2:9][CH2:10]2)[CH2:2][CH2:3]1.[F:28][c:29]1[cH:30][cH:31][c:32]([CH:35]([C:36](=[O:37])[OH:38])[CH3:39])[cH:33][cH:34]1>>[CH:1]1([CH2:4][N:5]2[CH2:6][CH2:7][CH:8]([C:11](=[O:12])[N:13]3[CH2:14][CH:15]([c:20]4[cH:21][c:22]([Cl:27])[c:23]([Cl:26])[cH:24][cH:25]4)[CH:16]([N:18]([CH3:19])[C:36]([CH:35]([c:32]4[cH:31][cH:30][c:29]([F:28])[cH:34][cH:33]4)[CH3:39])=[O:38])[CH2:17]3)[CH2:9][CH2:10]2)[CH2:2][CH2:3]1

참가 물질

3

반응물 2

HCID 27239152-(4-Fluorophenyl)propionic acidHCID 67025771(1-cyclopropylmethyl-piperidin-4-yl)-[(3SR,4RS)-3-(3,4-dichloro-phenyl)-4-methylamino-pyrrolidin-1-yl]-methanone

생성물 1

HCID 67025691N-[(3RS,4SR)-1-(1-cyclopropylmethyl-piperidine-4-carbonyl)-4-(3,4-dichloro-phenyl)-pyrrolidin-3-yl]-2-(4-fluoro-phenyl)-N-methyl-propionamide

출처 및 근거

ORD 기록
ord-5d228007e26b4e77b243e7dc5e132822
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

연결된 노트

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