Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Tetrahydrofuran → Methyl 4-hydroxy-2-methoxybenzoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Tetrahydrofuran | HCID 8028 | — |
| 반응물 | 4-Benzyloxy-2-methoxybenzoic acid methyl ester | HCID 10826039 | — |
| 촉매 | HCID 178418390 | HCID 178418390 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | Methyl 4-hydroxy-2-methoxybenzoate | HCID 12532676 | 98% |
반응 단계
To a solution of methyl 4-benzyloxy-2-methoxybenzoate (3.08 g) in methanol (5 mL)/tetrahydrofuran (7.5 mL) was added 10% palladium-carbon (0.3 g) at room temperature under an atmosphere of argon, and the mixture was stirred at that temperature for 2 hrs under an atmosphere of hydrogen. The catalyst was removed by filtration, and the filtrate was concentrated in vacuo to afford the title compound (2.02 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07423185B2 |
| 출처 데이터셋 | uspto-grants-2008_09 |
| ORD ID | ord-cac98ee240c347b09e50e6d4c18e0653 |
| 출처 메모 | uspto-grants-2008_09 |