Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-methyl-N-(4-{[4-(methylamino)-3-nitrophenyl]oxy}pyridin-2-yl)piperidine-4-carboxamide → N-(4-{[3-amino-4-(methylamino)phenyl]oxy}pyridin-2-yl)-1-methylpiperidine-4-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-methyl-N-(4-{[4-(methylamino)-3-nitrophenyl]oxy}pyridin-2-yl)piperidine-4-carboxamide | HCID 69003266 | — |
| 촉매 | Lindlars catalyst | HCID 131709914 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | N-(4-{[3-amino-4-(methylamino)phenyl]oxy}pyridin-2-yl)-1-methylpiperidine-4-carboxamide | HCID 69004595 | — |
반응 단계
The mixture containing 1-methyl-N-(4-{[4-(methylamino)-3-nitrophenyl]oxy}-pyridin-2-yl)piperidine-4-carboxamide in methanol with catalytic amount of Lindlar's catalyst was hydrogenated to yield N-(4-{[3-amino-4-(methylamino)phenyl]oxy}pyridin-2-yl)-1-methylpiperidine-4-carboxamide. MS: MH+=356.2.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07423150B2 |
| 출처 데이터셋 | uspto-grants-2008_09 |
| ORD ID | ord-aa4cd8e70394467a8ba26addc87009b5 |
| 출처 메모 | uspto-grants-2008_09 |