Dichloromethane → 7-(2-{[4-(1-Piperazinyl)-1,2,5-thiadiazol-3-yl]oxy}ethoxy)-2H-chromen-2-one

반응식

[Cl:41][CH2:42][Cl:43].[O:1]=[c:2]1[o:3][c:4]2[cH:5][c:6]([O:12][CH2:13][CH2:14][O:15][c:16]3[c:17]([N:21]4[CH2:22][CH2:23][N:24]([C:27]([O:28][C:29]([CH3:30])([CH3:31])[CH3:32])=[O:33])[CH2:25][CH2:26]4)[n:18][s:19][n:20]3)[cH:7][cH:8][c:9]2[cH:10][cH:11]1.[OH:34][C:35]([C:36]([F:37])([F:38])[F:39])=[O:40]>>[O:1]=[c:2]1[o:3][c:4]2[cH:5][c:6]([O:12][CH2:13][CH2:14][O:15][c:16]3[c:17]([N:21]4[CH2:22][CH2:23][NH:24][CH2:25][CH2:26]4)[n:18][s:19][n:20]3)[cH:7][cH:8][c:9]2[cH:10][cH:11]1

참가 물질

반응물 3

HCID 6344Dichloromethane

HCID 6422Trifluoroacetic acid

HCID 22036300tert-Butyl 4-(4-{2-[(2-oxo-2H-chromen-7-yl)oxy]ethoxy}-1,2,5-thiadiazol-3-yl)-1-piperazinecarboxylate

생성물 1

HCID 220362437-(2-{[4-(1-Piperazinyl)-1,2,5-thiadiazol-3-yl]oxy}ethoxy)-2H-chromen-2-one

출처 및 근거

ORD 기록: ord-6db8b550cb8c460690b5e7f75c6a4032
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

반응 노트

불러오는 중…