Dimethylformamide → N-(6-(5-cyanopyrazin-2-ylamino)-4-(1-Boc-piperidin-4-ylmethylamino)pyridin-3-yl)ethanesulfonamide

반응식

[CH2:8]([CH3:9])[S:10](=[O:11])(=[O:12])[Cl:13].[CH3:1][CH2:2][N:3]([CH2:4][CH3:5])[CH2:6][CH3:7].[NH2:14][c:15]1[c:16]([NH:30][CH2:31][CH:32]2[CH2:33][CH2:34][N:35]([C:38](=[O:39])[O:40][C:41]([CH3:42])([CH3:43])[CH3:44])[CH2:36][CH2:37]2)[cH:17][c:18]([NH:21][c:22]2[n:23][cH:24][c:25]([C:28]#[N:29])[n:26][cH:27]2)[n:19][cH:20]1.[O:45]=[CH:46][N:47]([CH3:48])[CH3:49]>>[CH2:8]([CH3:9])[S:10](=[O:11])(=[O:12])[NH:14][c:15]1[c:16]([NH:30][CH2:31][CH:32]2[CH2:33][CH2:34][N:35]([C:38](=[O:39])[O:40][C:41]([CH3:42])([CH3:43])[CH3:44])[CH2:36][CH2:37]2)[cH:17][c:18]([NH:21][c:22]2[n:23][cH:24][c:25]([C:28]#[N:29])[n:26][cH:27]2)[n:19][cH:20]1