Dichloromethane → 4-[2-Cyclopentyl-1-(5-methoxy-thiazolo[5,4-b]pyridin-2-ylcarbamoyl)-ethyl]-benzenesulfonyl chloride

반응식

[CH:6]1([CH2:11][CH:12]([C:13](=[O:14])[NH:15][c:16]2[s:17][c:18]3[n:19][c:20]([O:25][CH3:26])[cH:21][cH:22][c:23]3[n:24]2)[c:27]2[cH:28][cH:29][cH:30][cH:31][cH:32]2)[CH2:7][CH2:8][CH2:9][CH2:10]1.[Cl:1][S:2](=[O:3])(=[O:4])[OH:5].[Cl:33][CH2:34][Cl:35]>>[Cl:1][S:2](=[O:3])(=[O:5])[c:30]1[cH:29][cH:28][c:27]([CH:12]([CH2:11][CH:6]2[CH2:7][CH2:8][CH2:9][CH2:10]2)[C:13](=[O:14])[NH:15][c:16]2[s:17][c:18]3[n:19][c:20]([O:25][CH3:26])[cH:21][cH:22][c:23]3[n:24]2)[cH:32][cH:31]1

참가 물질

반응물 3

HCID 6344Dichloromethane

HCID 24638Chlorosulfonic acid

HCID 872411633-cyclopentyl-N-(5-methoxy-[1,3]thiazolo[5,4-b]pyridin-2-yl)-2-phenylpropanamide

생성물 1

HCID 444741674-[2-Cyclopentyl-1-(5-methoxy-thiazolo[5,4-b]pyridin-2-ylcarbamoyl)-ethyl]-benzenesulfonyl chloride

출처 및 근거

ORD 기록: ord-911b57da068f4ec7ad1c4a483006bb4d
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

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