Dichloromethane → 8-Chloro-3-(chloromethyl)-2-(2-trifluoromethylphenyl)quinoline

반응식

[Cl:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[cH:7][c:8]([CH2:22][OH:23])[c:9](-[c:12]3[c:13]([C:18]([F:19])([F:20])[F:21])[cH:14][cH:15][cH:16][cH:17]3)[n:10][c:11]12.[Cl:28][CH2:29][Cl:30].[S:24]([Cl:25])([Cl:26])=[O:27]>>[Cl:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[cH:7][c:8]([CH2:22][Cl:26])[c:9](-[c:12]3[c:13]([C:18]([F:19])([F:20])[F:21])[cH:14][cH:15][cH:16][cH:17]3)[n:10][c:11]12

참가 물질

반응물 3

HCID 6344Dichloromethane

HCID 24386Thionyl Chloride

HCID 57556184(8-Chloro-2-(2-trifluoromethylphenyl)quinolin-3-yl)methanol

생성물 1

HCID 575561498-Chloro-3-(chloromethyl)-2-(2-trifluoromethylphenyl)quinoline

출처 및 근거

ORD 기록: ord-fe641d3318d14156887e34fd4ca1cffc
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

반응 노트

불러오는 중…