2,2,3,3,3-Pentafluoropropylamine → HCID 58972497, 화합물

HRID 31004

반응식

HRID 31004 반응식
[CH2:1]([O:8][CH2:9][CH2:10][N:11]1[C:17](=[O:18])[C@@H:16]([NH:19][C:20](=[O:25])[CH2:21][C:22](O)=[O:23])[C:15]2[CH:26]=[CH:27][CH:28]=[CH:29][C:14]=2[C:13]2[CH:30]=[CH:31][CH:32]=[CH:33][C:12]1=2)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[F:34][C:35]([F:42])([C:38]([F:41])([F:40])[F:39])[CH2:36][NH2:37]>>[CH2:1]([O:8][CH2:9][CH2:10][N:11]1[C:17](=[O:18])[C@@H:16]([NH:19][C:20](=[O:25])[CH2:21][C:22]([NH:37][CH2:36][C:35]([F:42])([F:34])[C:38]([F:41])([F:40])[F:39])=[O:23])[C:15]2[CH:26]=[CH:27][CH:28]=[CH:29][C:14]=2[C:13]2[CH:30]=[CH:31][CH:32]=[CH:33][C:12]1=2)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

참가 물질

3

반응물 2

HCID 790022,2,3,3,3-PentafluoropropylamineHCID 58972481N-[(S)-5-(2-benzyloxy-ethyl)-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl]-malonamic acid

생성물 1

HCID 58972497HCID 58972497, 화합물

실험 절차

Using N—[(S)-5-(2-benzyloxy-ethyl)-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl]-malonamic acid and N-(2,2,3,3,3-pentafluoro-propyl amine, the title compound was prepared in the same manner as example 1c (73%). White solid. MS: m/e=576(M+H+).

출처 및 근거

ORD 기록
ord-8dd64c2a938d4775b30d3f48c02a9bef
출처 데이터셋
uspto-grants-2008_09
특허 번호
US07425551B2

연결된 노트

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