(S)-7-amino-5-(2-benzyloxy-ethyl)-5H,7H-dibenzo[b,d]azepin-6-one → HCID 58972500, 화합물

HRID 31042노트

반응식

HRID 31042 반응식
[NH2:1][C@@H:2]1[C:8](=[O:9])[N:7]([CH2:10][CH2:11][O:12][CH2:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[C:6]2[CH:20]=[CH:21][CH:22]=[CH:23][C:5]=2[C:4]2[CH:24]=[CH:25][CH:26]=[CH:27][C:3]1=2.[OH:28][C@@:29]([CH3:41])([C:33]([NH:35][CH2:36][C:37]([F:40])([F:39])[F:38])=[O:34])[C:30](O)=[O:31]>>[CH2:13]([O:12][CH2:11][CH2:10][N:7]1[C:8](=[O:9])[C@@H:2]([NH:1][C:30](=[O:31])[C@:29]([OH:28])([CH3:41])[C:33]([NH:35][CH2:36][C:37]([F:38])([F:39])[F:40])=[O:34])[C:3]2[CH:27]=[CH:26][CH:25]=[CH:24][C:4]=2[C:5]2[CH:23]=[CH:22][CH:21]=[CH:20][C:6]1=2)[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

참가 물질

3

반응물 2

HCID 58972512(S)-7-amino-5-(2-benzyloxy-ethyl)-5H,7H-dibenzo[b,d]azepin-6-oneHCID 86615291(S)-2-hydroxy-2-methyl-N-(2,2,2-trifluoro-ethyl)-malonamic acid

생성물 1

HCID 58972500HCID 58972500, 화합물

실험 절차

Using (S)-7-amino-5-(2-benzyloxy-ethyl)-5H,7H-dibenzo[b,d]azepin-6-one and (S)-2-hydroxy-2-methyl-N-(2,2,2-trifluoro-ethyl)-malonamic acid, the title compound was prepared in the same manner as described for example 1c. Colorless, amorphous solid (91%). MS: m/e=556(M+H+).

출처 및 근거

ORD 기록
ord-b971b091c0a44304a1f278cf6e26f191
출처 데이터셋
uspto-grants-2008_09
특허 번호
US07425551B2

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