N-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanesulfonamide → 4-(5-chloro-7-morpholinothiazolo[5,4-d]pyrimidin-2-yl)-N-methylsulfonylbenzenamine

반응식

[CH3:18][S:19](=[O:20])(=[O:21])[NH:22][c:23]1[cH:24][cH:25][c:26]([B:29]2[O:30][C:31]([CH3:32])([CH3:33])[C:34]([CH3:35])([CH3:36])[O:37]2)[cH:27][cH:28]1.[Cl:1][c:2]1[n:3][c:4]([N:12]2[CH2:13][CH2:14][O:15][CH2:16][CH2:17]2)[c:5]2[c:6]([n:7]1)[s:8][c:9]([I:11])[n:10]2>>[Cl:1][c:2]1[n:3][c:4]([N:12]2[CH2:13][CH2:14][O:15][CH2:16][CH2:17]2)[c:5]2[c:6]([n:7]1)[s:8][c:9](-[c:26]1[cH:25][cH:24][c:23]([NH:22][S:19]([CH3:18])(=[O:20])=[O:21])[cH:28][cH:27]1)[n:10]2

참가 물질

반응물 2

HCID 16217653N-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanesulfonamide

HCID 252102844-(5-Chloro-2-iodothiazolo[5,4-d]pyrimidin-7-yl)morpholine

생성물 1

HCID 866300754-(5-chloro-7-morpholinothiazolo[5,4-d]pyrimidin-2-yl)-N-methylsulfonylbenzenamine

출처 및 근거

ORD 기록: ord-1b796fb92453459bb18190f9abb56825
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

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