1,4-Dibromobenzene → 2-[[(4-Bromophenyl)-(2,4-difluorophenyl)methyl]amino]-4-methylpentan-1-ol

반응식

[Br:1][c:2]1[cH:3][cH:4][c:5]([Br:6])[cH:7][cH:8]1.[CH3:9][CH2:10][CH2:11][CH2:12][Li:13].[F:14][c:15]1[c:16]([CH:17]=[N:18][CH:19]([CH2:20][OH:21])[CH2:22][CH:23]([CH3:24])[CH3:25])[cH:26][cH:27][c:28]([F:30])[cH:29]1>>[c:2]1([CH:17]([c:16]2[c:15]([F:14])[cH:29][c:28]([F:30])[cH:27][cH:26]2)[NH:18][CH:19]([CH2:20][OH:21])[CH2:22][CH:23]([CH3:24])[CH3:25])[cH:3][cH:4][c:5]([Br:6])[cH:7][cH:8]1

참가 물질

반응물 3

HCID 78041,4-Dibromobenzene

HCID 574469542-[(2,4-Difluorobenzylidene)-amino]-4-methylpentan-1-ol

HCID 178418339Butyllithium

생성물 1

HCID 772621512-[[(4-Bromophenyl)-(2,4-difluorophenyl)methyl]amino]-4-methylpentan-1-ol

출처 및 근거

ORD 기록: ord-c9047d7e6151493a8e4a92cf0d364bef
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

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