Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dichloromethane → 4-bromo-N'-(2,2-dimethylpropanoyl)benzohydrazide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dichloromethane | HCID 6344 | — |
| 반응물 | Ammonium Chloride | HCID 25517 | — |
| 반응물 | 4-Bromobenzoyl chloride | HCID 68515 | — |
| 반응물 | tert-Butyl carbazate | HCID 70091 | — |
| 반응물 | Diisopropylethylamine | HCID 81531 | — |
| 생성물 | 4-bromo-N'-(2,2-dimethylpropanoyl)benzohydrazide | HCID 4782693 | — |
반응 단계
t-Butyloxycarbonylhydrazine (1.26 g) was added portionwise to a solution of 4-bromobenzoyl chloride (2.0 g), and DIPEA (2.37 ml) in DCM (20 ml) and the reaction stirred at room temperature for 18 hours. Ammonium chloride solution was added, the organic phase was separated, dried and the solvent evaporated under vacuum to give 4-bromo-benzoic acid N′-(2,2-dimethyl-propionyl)-hydrazide.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07425555B2 |
| 출처 데이터셋 | uspto-grants-2008_09 |
| ORD ID | ord-8132fc3f3dc447e5b26609efe5f81896 |
| 출처 메모 | uspto-grants-2008_09 |