Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-{[5-(4-Iodophenyl)-1,3,4-oxadiazol-2-yl]methyl}piperidine → 6-Methyl-4'-(5-piperidin-1-ylmethyl-[1,3,4]oxadiazol-2-yl)biphenyl-3-carboxylic acid cyclopropylamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-{[5-(4-Iodophenyl)-1,3,4-oxadiazol-2-yl]methyl}piperidine | HCID 7096895 | — |
| 반응물 | N-cyclopropyl-4-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide | HCID 21914577 | — |
| 생성물 | 6-Methyl-4'-(5-piperidin-1-ylmethyl-[1,3,4]oxadiazol-2-yl)biphenyl-3-carboxylic acid cyclopropylamide | HCID 10432064 | — |
반응 단계
Example 13 was prepared from 1-[5-(4-iodophenyl)-[1,3,4]oxadiazol-2-ylmethyl]-piperidine (intermediate 9) and N-cyclopropyl-4-methyl-3-(4,4,5,5-tetramethyl-[1,3,2]-dioxaborolan-2-yl)benzamide (Intermediate 17).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07425555B2 |
| 출처 데이터셋 | uspto-grants-2008_09 |
| ORD ID | ord-cff0c77640ac402cb2e8fb83c3e78f33 |
| 출처 메모 | uspto-grants-2008_09 |