Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-(4-Bromo-3-methylphenyl)-5-methyl-1,2,4-oxadiazole → 6,2'-Dimethyl-4'-(5-methyl-[1,2,4]oxadiazol-3-yl)-biphenyl-3-carboxylic acid (3-morpholin-4-yl-phenyl)amide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-(4-Bromo-3-methylphenyl)-5-methyl-1,2,4-oxadiazole | HCID 12121944 | — |
| 반응물 | 4-methyl-N-[3-(4-morpholinyl)phenyl]-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)benzamide | HCID 59791521 | — |
| 용매 | Isopropanol | HCID 3776 | — |
| 생성물 | 6,2'-Dimethyl-4'-(5-methyl-[1,2,4]oxadiazol-3-yl)-biphenyl-3-carboxylic acid (3-morpholin-4-yl-phenyl)amide | HCID 58629800 | — |
반응 단계
Example 32 was prepared using 3-(4-bromo-3-methylphenyl)-5-methyl-[1,2,4]oxadiazole and 4-methyl-N-(3-morpholin-4-yl-phenyl)-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl) -benzamide (Intermediate 5) with propan-2-ol as the solvent.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07425555B2 |
| 출처 데이터셋 | uspto-grants-2008_09 |
| ORD ID | ord-8c84d73a086a41d6ade84a5fde6de898 |
| 출처 메모 | uspto-grants-2008_09 |