Sodium Bicarbonate → HCID 178498471, 화합물

HRID 31529

반응식

HRID 31529 반응식
[N+:1]([C:4]1[CH:5]=[C:6]([C:9]([OH:11])=[O:10])[NH:7][N:8]=1)([O-:3])=[O:2].[C:12](=O)(O)[O-].[Na+]>CO.S(=O)(=O)(O)O>[CH3:12][O:10][C:9]([C:6]1[NH:7][N:8]=[C:4]([N+:1]([O-:3])=[O:2])[CH:5]=1)=[O:11]

참가 물질

4

반응물 2

HCID 516892Sodium BicarbonateHCID 178524578HCID 178524578, 화합물

생성물 1

HCID 178498471HCID 178498471, 화합물

시약·촉매·용매 1

HCID 18363649Sulfuric acid methanol용매

실험 절차

A solution of 5-Nitro-2H-pyrazole-3-carboxylic acid (5 gm, 32 mmol) in 100 ml of 2% sulfuric acid methanol was refluxed for 20 hours. The mixture was cooled to room temperature and added to saturated sodium bicarbonate. The mixture was extracted with ethyl acetate three times to obtain 3.59 gm of title product after drying over magnesium sulfate, filtering and evaporating to dryness. ESI M+1=171.

후처리

  1. extractionThe mixture was extracted with ethyl acetate three times

출처 및 근거

ORD 기록
ord-22a35fe448e645d49e111277870338bb
출처 데이터셋
uspto-grants-2008_09
특허 번호
US07425640B2

연결된 노트

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