Cyanocyclobutane → (1-Cyclobutyl-2,6,7-trioxabicyclo[2.2.2]oct-4-yl)methanol

HRID 31652노트

반응식

[CH:1]1([C:4]23[O:11][CH2:10][C:7]([CH2:12][OH:13])([CH2:8][O:9]2)[CH2:6][O:5]3)[CH2:3][CH2:2]1.[CH:14]1(C#N)CCC1>>[CH:1]1([C:4]23[O:5][CH2:6][C:7]([CH2:12][OH:13])([CH2:8][O:9]2)[CH2:10][O:11]3)[CH2:3][CH2:2][CH2:14]1

참가 물질

반응물 2

HCID 78148Cyanocyclobutane

HCID 59792605(1-Cyclopropyl-2,6,7-trioxabicyclo[2.2.2]oct-4-yl)methanol

생성물 1

HCID 59792382(1-Cyclobutyl-2,6,7-trioxabicyclo[2.2.2]oct-4-yl)methanol수율 51%

실험 절차

The same procedure as in the steps (37a) to (37c) of Example 37 was repeated using cyclobutanecarbonitrile to obtain the title compound (15 g, total yield: 51%) as a light yellow oil.

출처 및 근거

ORD 기록: ord-8161260e18284c7b83865735b591d5c1
출처 데이터셋: uspto-grants-2008_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07425634B2

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