2-Amino-4,6-dichloropyrimidine → 6-Chloro-N4-[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]pyrimidine-2,4-diamine

HRID 316595

반응식

HRID 316595 반응식
[Cl:19][c:20]1[n:21][c:22]([NH2:27])[n:23][c:24]([Cl:26])[cH:25]1.[F:1][c:2]1[cH:3][c:4]([NH2:5])[cH:6][cH:7][c:8]1[O:9][c:10]1[c:11]2[c:12]([n:13][cH:14][cH:15]1)[nH:16][cH:17][cH:18]2>>[F:1][c:2]1[cH:3][c:4]([NH:5][c:24]2[n:23][c:22]([NH2:27])[n:21][c:20]([Cl:19])[cH:25]2)[cH:6][cH:7][c:8]1[O:9][c:10]1[c:11]2[c:12]([n:13][cH:14][cH:15]1)[nH:16][cH:17][cH:18]2

참가 물질

3

반응물 2

HCID 655222-Amino-4,6-dichloropyrimidineHCID 160379654-((1H-Pyrrolo[2,3-B]pyridin-4-YL)oxy)-3-fluoroaniline

생성물 1

HCID 587332416-Chloro-N4-[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]pyrimidine-2,4-diamine

출처 및 근거

ORD 기록
ord-5c09b0946dc342529cc4b58aa28d1258
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

연결된 노트

불러오는 중…