반응식
ClC1C=C(Cl)C=CC=1C1C(N2C=CN=C2)=CN=C(CCN)N=1.Cl[C:24]1[N:29]=[CH:28][C:27]([C:30](=[O:32])[CH3:31])=[CH:26][CH:25]=1.[Cl:33][C:34]1[CH:39]=[C:38]([Cl:40])[CH:37]=[CH:36][C:35]=1[C:41]1[C:46]([C:47]2[NH:48][CH:49]=[CH:50][N:51]=2)=[CH:45][N:44]=[C:43]([NH:52][CH2:53][CH2:54][NH:55]C2C=CC([N+]([O-])=O)=C(OC)N=2)[N:42]=1>>[Cl:33][C:34]1[CH:39]=[C:38]([Cl:40])[CH:37]=[CH:36][C:35]=1[C:41]1[C:46]([C:47]2[NH:51][CH:50]=[CH:49][N:48]=2)=[CH:45][N:44]=[C:43]([NH:52][CH2:53][CH2:54][NH:55][C:24]2[N:29]=[CH:28][C:27]([C:30](=[O:32])[CH3:31])=[CH:26][CH:25]=2)[N:42]=1참가 물질
4
반응물 3
생성물 1
실험 절차
1-{6-[(2-{[4-(2,4-dichlorophenyl)-5-imidazolylpyrimidin-2-yl]amino}ethyl)-amino]-3-pyridyl}ethan-1-one was prepared from [4-(2,4-dichlorophenyl)-5-imidazol-1-ylpyrimidin-2-yl]ethylamine and 1-(6-chloro-3-pyridyl)-ethanone (prepared as described in Tetrahedron 48:9233 (1992)) in accordance to the procedure described above for the preparation of [4-(2,4-dichlorophenyl)-5-imidazol-2-ylpyrimidin-2-yl]{2-[(6-methoxy-5-nitro(2-pyridyl))amino]ethyl}amine.
출처 및 근거
- ORD 기록
- ord-52330fd33fce41b5a6eeccffee9d0b7b
- 출처 데이터셋
- uspto-grants-2008_09
- 특허 번호
- US07425557B2
연결된 노트
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