(6-Chloro-3-nitro(2-pyridyl))(methylsulfonyl)amine → {6-[(2-{[4-(2,4-Dichlorophenyl)-5-imidazolylpyrimidin-2-yl]amino}ethyl)amino]-3-nitro(2-pyridyl)}(methylsulfonyl)amine

HRID 31835

반응식

HRID 31835 반응식
ClC1C=C(Cl)C=CC=1C1C(C2NC=CN=2)=CN=C(CCN)N=1.Cl[C:24]1[N:29]=[C:28]([NH:30][S:31]([CH3:34])(=[O:33])=[O:32])[C:27]([N+:35]([O-:37])=[O:36])=[CH:26][CH:25]=1.[Cl:38][C:39]1[CH:44]=[C:43]([Cl:45])[CH:42]=[CH:41][C:40]=1[C:46]1[C:51]([C:52]2[NH:53][CH:54]=[CH:55][N:56]=2)=[CH:50][N:49]=[C:48]([NH:57][CH2:58][CH2:59][NH:60]C2C=CC([N+]([O-])=O)=C(OC)N=2)[N:47]=1>>[Cl:38][C:39]1[CH:44]=[C:43]([Cl:45])[CH:42]=[CH:41][C:40]=1[C:46]1[C:51]([C:52]2[NH:56][CH:55]=[CH:54][N:53]=2)=[CH:50][N:49]=[C:48]([NH:57][CH2:58][CH2:59][NH:60][C:24]2[N:29]=[C:28]([NH:30][S:31]([CH3:34])(=[O:33])=[O:32])[C:27]([N+:35]([O-:37])=[O:36])=[CH:26][CH:25]=2)[N:47]=1

참가 물질

4

반응물 3

HCID 22142577(6-Chloro-3-nitro(2-pyridyl))(methylsulfonyl)amineHCID 22142635[4-(2,4-Dichlorophenyl)-5-imidazol-2-ylpyrimidin-2-yl]{2-[(6-methoxy-5-nitro(2-pyridyl)) amino]ethyl}amineHCID 542317734-(2,4-Dichlorophenyl)-5-imidazolylpyrimidin-2-ylethylamine

생성물 1

HCID 22142954{6-[(2-{[4-(2,4-Dichlorophenyl)-5-imidazolylpyrimidin-2-yl]amino}ethyl)amino]-3-nitro(2-pyridyl)}(methylsulfonyl)amine

실험 절차

{6-[(2-{[4-(2,4-dichlorophenyl)-5-imidazol-2-ylpyrimidin-2-yl]amino}ethyl)-amino]-3-nitro(2-pyridyl)}(methylsulfonyl)amine was prepared from [4-(2,4-dichlorophenyl)-5-imidazol-2-ylpyrimidin-2-ylethylamine and (6-chloro-3-nitro(2-pyridyl))(methylsulfonyl)amine in accordance with the procedure described above for the preparation of [4-(2,4-dichlorophenyl)-5-imidazol-2-ylpyrimidin-2-yl]{2-[(6-methoxy-5-nitro(2-pyridyl))amino]ethyl}amine.

출처 및 근거

ORD 기록
ord-c94a840f92f046628fffad8d7714adac
출처 데이터셋
uspto-grants-2008_09
특허 번호
US07425557B2

연결된 노트

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