4-Amino-2-chloropyrimidine-5-carbonitrile → HCID 57221537, 화합물

HRID 31845

반응식

HRID 31845 반응식
ClC1C=C(Cl)C=CC=1C1C(N2C=CN=C2)=CN=C(CCN)N=1.Cl[C:24]1[N:29]=[C:28]([NH2:30])[C:27]([C:31]#[N:32])=[CH:26][N:25]=1.[Cl:33][C:34]1[CH:39]=[C:38]([Cl:40])[CH:37]=[CH:36][C:35]=1[C:41]1[C:46]([C:47]2[NH:48][CH:49]=[CH:50][N:51]=2)=[CH:45][N:44]=[C:43]([NH:52][CH2:53][CH2:54][NH:55]C2C=CC([N+]([O-])=O)=C(OC)N=2)[N:42]=1>>[NH2:30][C:28]1[C:27]([C:31]#[N:32])=[CH:26][N:25]=[C:24]([NH:55][CH2:54][CH2:53][NH:52][C:43]2[N:42]=[C:41]([C:35]3[CH:36]=[CH:37][C:38]([Cl:40])=[CH:39][C:34]=3[Cl:33])[C:46]([C:47]3[NH:51][CH:50]=[CH:49][N:48]=3)=[CH:45][N:44]=2)[N:29]=1

참가 물질

4

반응물 3

HCID 28011664-Amino-2-chloropyrimidine-5-carbonitrileHCID 22142635[4-(2,4-Dichlorophenyl)-5-imidazol-2-ylpyrimidin-2-yl]{2-[(6-methoxy-5-nitro(2-pyridyl)) amino]ethyl}amineHCID 571748954-(2,4-Dichlorophenyl)-5-imidazol-1-ylpyrimidin-2-ylethylamine

생성물 1

HCID 57221537HCID 57221537, 화합물

실험 절차

4-amino-2-[(2-{[4-(2,4-dichlorophenyl)-5-imidazolylpyrimidin-2-yl]amino}ethyl)-amino]pyrimidine-5-carbonitrile was prepared from [4-(2,4-dichlorophenyl)-5-imidazol-1-ylpyrimidin-2-ylethylamine and 2-chloro-4-amino-5-cyanopyrimidine in accordance with the procedure described above for the preparation of [4-(2,4-dichlorophenyl)-5-imidazol-2-ylpyrimidin-2-yl]{2-[(6-methoxy-5-nitro(2-pyridyl))amino]ethyl}amine.

출처 및 근거

ORD 기록
ord-238d17b35ae34301b30c074ae1a9e5e9
출처 데이터셋
uspto-grants-2008_09
특허 번호
US07425557B2

연결된 노트

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