Isopropylamine → 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 23

HRID 3185

반응식

HRID 3185 반응식
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([Cl:8])[C:3]=1[C:9]1[C:20](=[O:21])[N:19]([CH3:22])[C:12]2[N:13]=[C:14](SC)[N:15]=[CH:16][C:11]=2[CH:10]=1.[CH:23]([NH2:26])([CH3:25])[CH3:24]>>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([Cl:8])[C:3]=1[C:9]1[C:20](=[O:21])[N:19]([CH3:22])[C:12]2[N:13]=[C:14]([NH:26][CH:23]([CH3:25])[CH3:24])[N:15]=[CH:16][C:11]=2[CH:10]=1

참가 물질

3

반응물 2

HCID 6363IsopropylamineHCID 107367016-(2,6-Dichlorophenyl)-8-methyl-2-(methylthio)pyrido[2,3-d]pyrimidin-7(8H)-one

생성물 1

HCID 53278702-aminopyrido[2,3-d]pyrimidin-7(8H)-one 23

실험 절차

This compound was prepared by a procedure similar to that described in Example 40 starting with 6-(2,6-dichlorophenyl)-8-methyl-2-methylsulfanyl-8H-pyrido[2,3-d]pyrimidin-7-one of Example 37 and isopropylamine; mp 194°-196° C.

후처리

  1. customThis compound was prepared by a procedure similar to

출처 및 근거

ORD 기록
ord-d04022b22bcd4100a137a9c7f735c157
출처 데이터셋
uspto-grants-1998_03
특허 번호
US05733914

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