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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 31876생성일: 2026년 10월 25일

4-(Trifluoromethyl)benzoyl chloride → 6-{[2-({5-Imidazol-2-yl-4-[4-(trifluoromethyl)phenyl]pyrimidin-2-yl}amino)ethyl]-amino}pyridine-3-carbonitrile

https://huagongshe.com/reaction/31876

반응식

참여 물질

역할이름HCID투입량
반응물4-(Trifluoromethyl)benzoyl chlorideHCID 67607—
반응물6-Chloro-3-pyridinecarbonitrileHCID 5152094—
반응물Chir-98023HCID 9847557—
생성물6-{[2-({5-Imidazol-2-yl-4-[4-(trifluoromethyl)phenyl]pyrimidin-2-yl}amino)ethyl]-amino}pyridine-3-carbonitrileHCID 22142493—

반응 단계

b 6-{[2-({5-imidazol-2-yl-4-[4-(trifluoromethyl)phenyl]pyrimidin-2-yl}amino)ethyl]-amino}pyridine-3-carbonitrile was prepared from 4-(trifluoromethyl)benzoyl chloride and 2-chloro-5-(cyano)pyridine using the general method for [4-(2,4-dichlorophenyl)-5-imidazol-2-ylpyrimidin-2-yl]{2-[(5-nitro(2-pyridyl))amino]ethyl}amine.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07425557B2
출처 데이터셋uspto-grants-2008_09
ORD IDord-5644389144a8421785b01900d6826ba8
출처 메모uspto-grants-2008_09