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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 31891생성일: 2026년 10월 25일

2-Chloro-5-(trifluoromethyl)pyridine → {4-[4-Fluoro-2-(trifluoromethyl)phenyl]-5-imidazol-2-ylpyrimidin-2-yl}(2-{[5-(trifluoromethyl)(2-pyridyl)]amino}ethyl)amine

https://huagongshe.com/reaction/31891

반응식

참여 물질

역할이름HCID투입량
반응물2-Chloro-5-(trifluoromethyl)pyridineHCID 92342—
반응물4-Fluoro-2-(trifluoromethyl)benzoyl chlorideHCID 605680—
반응물Chir-98023HCID 9847557—
생성물{4-[4-Fluoro-2-(trifluoromethyl)phenyl]-5-imidazol-2-ylpyrimidin-2-yl}(2-{[5-(trifluoromethyl)(2-pyridyl)]amino}ethyl)amineHCID 22142758—

반응 단계

{4-[4-fluoro-2-(trifluoromethyl)phenyl]-5-imidazol-2-ylpyrimidin-2-yl}(2-{[5-(trifluoromethyl)(2-pyridyl)]amino}ethyl)amine was prepared from 4-fluoro-2-(trifluoromethyl)benzoyl chloride and 2-chloro-5-(trifluoromethyl)pyridine using the general method for [4-(2,4-dichlorophenyl)-5-imidazol-2-ylpyrimidin-2-yl]{2-[(5-nitro(2-pyridyl))amino]ethyl}amine.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07425557B2
출처 데이터셋uspto-grants-2008_09
ORD IDord-5ba8b4976bb840ecae19d4a9ed2ef649
출처 메모uspto-grants-2008_09