반응식
[F:1][C:2]1[CH:10]=[C:9]([C:11]([F:14])([F:13])[F:12])[CH:8]=[CH:7][C:3]=1[C:4](Cl)=O.Cl[C:16]1[CH:21]=[CH:20][C:19]([C:22]#[N:23])=[CH:18][N:17]=1.ClC1C=C(Cl)C=CC=1C1[C:37]([C:38]2[NH:39][CH:40]=[CH:41][N:42]=2)=[CH:36][N:35]=[C:34]([NH:43][CH2:44][CH2:45][NH:46]C2C=CC([N+]([O-])=O)=CN=2)[N:33]=1>>[F:1][C:2]1[CH:10]=[C:9]([C:11]([F:14])([F:13])[F:12])[CH:8]=[CH:7][C:3]=1[C:4]1[C:37]([C:38]2[NH:39][CH:40]=[CH:41][N:42]=2)=[CH:36][N:35]=[C:34]([NH:43][CH2:44][CH2:45][NH:46][C:16]2[N:17]=[CH:18][C:19]([C:22]#[N:23])=[CH:20][CH:21]=2)[N:33]=1참가 물질
4
실험 절차
6-{[2-({4-[2-fluoro-4-(trifluoromethyl)phenyl]-5-imidazol-2-ylpyrimidin-2-yl}amino)ethyl]amino}pyridine-3-carbonitrile was prepared from 2-fluoro-4-(trifluoromethyl)benzoyl chloride and 2-chloro-5-(cyano)pyridine using the general method for [4-(2,4-dichlorophenyl)-5-imidazol-2-ylpyrimidin-2-yl]{2-[(5-nitro(2-pyridyl))amino]ethyl}amine.
출처 및 근거
- ORD 기록
- ord-ff3164a08e7c405abae323144533f98f
- 출처 데이터셋
- uspto-grants-2008_09
- 특허 번호
- US07425557B2
연결된 노트
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