Ethyl (-)-lactate triflate → Tert-butyl 3-(1(r,s)-ethoxycarbonylethoxy)-4-{4-[3-(2-methoxybenzyloxy)propoxy]-phenyl}piperidine-1-carboxylate

반응식

[F:1][C:2]([F:3])([F:4])[S:5]([O:6][CH:7]([C:8](=[O:9])[O:10][CH2:11][CH3:12])[CH3:13])(=[O:14])=[O:15].[OH:16][CH:17]1[CH2:18][N:19]([C:43](=[O:44])[O:45][C:46]([CH3:47])([CH3:48])[CH3:49])[CH2:20][CH2:21][CH:22]1[c:23]1[cH:24][cH:25][c:26]([O:29][CH2:30][CH2:31][CH2:32][O:33][CH2:34][c:35]2[c:36]([O:41][CH3:42])[cH:37][cH:38][cH:39][cH:40]2)[cH:27][cH:28]1>>[O:6]([CH:7]([C:8](=[O:9])[O:10][CH2:11][CH3:12])[CH3:13])[CH:17]1[CH2:18][N:19]([C:43](=[O:44])[O:45][C:46]([CH3:47])([CH3:48])[CH3:49])[CH2:20][CH2:21][CH:22]1[c:23]1[cH:24][cH:25][c:26]([O:29][CH2:30][CH2:31][CH2:32][O:33][CH2:34][c:35]2[c:36]([O:41][CH3:42])[cH:37][cH:38][cH:39][cH:40]2)[cH:27][cH:28]1

참가 물질

반응물 2

HCID 4251232Ethyl (-)-lactate triflate

HCID 15546933Tert-butyl 3-hydroxy-4-{4-[3-(2-methoxybenzyloxy) propoxy]phenyl}piperidine-1-carboxylate

생성물 1

HCID 68501234Tert-butyl 3-(1(r,s)-ethoxycarbonylethoxy)-4-{4-[3-(2-methoxybenzyloxy)propoxy]-phenyl}piperidine-1-carboxylate

출처 및 근거

ORD 기록: ord-b90f249b3766478c9beeb05742892be5
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

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