[6-(2,4-Dichlorophenyl)-5-imidazolyl(2-pyridyl)]{2-[(5-nitro(2-pyridyl))amino]ethyl}amine → 6-[(2-{[6-(2,4-Dichlorophenyl)-5-imidazolyl-2-pyridyl]amino}ethyl)amino]-pyridine-3-carbonitrile

HRID 31920

반응식

HRID 31920 반응식
[NH2:1][CH2:2]CNC1N=CC(C#N)=CC=1.[Cl:13][C:14]1[CH:19]=[C:18]([Cl:20])[CH:17]=[CH:16][C:15]=1[C:21]1[N:26]=[C:25]([NH:27][CH2:28][CH2:29][NH:30][C:31]2[CH:36]=[CH:35][C:34]([N+]([O-])=O)=[CH:33][N:32]=2)[CH:24]=[CH:23][C:22]=1[C:40]1[NH:41][CH:42]=[CH:43][N:44]=1>>[Cl:13][C:14]1[CH:19]=[C:18]([Cl:20])[CH:17]=[CH:16][C:15]=1[C:21]1[N:26]=[C:25]([NH:27][CH2:28][CH2:29][NH:30][C:31]2[N:32]=[CH:33][C:34]([C:2]#[N:1])=[CH:35][CH:36]=2)[CH:24]=[CH:23][C:22]=1[C:40]1[NH:44][CH:43]=[CH:42][N:41]=1

참가 물질

3

반응물 2

HCID 10238712[6-(2,4-Dichlorophenyl)-5-imidazolyl(2-pyridyl)]{2-[(5-nitro(2-pyridyl))amino]ethyl}amineHCID 113694056-[(2-Aminoethyl)amino]pyridine-3-carbonitrile

생성물 1

HCID 101275186-[(2-{[6-(2,4-Dichlorophenyl)-5-imidazolyl-2-pyridyl]amino}ethyl)amino]-pyridine-3-carbonitrile

실험 절차

6-[(2-{[6-(2,4-dichlorophenyl)-5-imidazol-2-yl-2-pyridyl]amino}ethyl)amino]-pyridine-3-carbonitrile was prepared from 6-[(2-aminoethyl)amino]pyridine-3-carbonitrile using the general method for [6-(2,4-dichlorophenyl)-5-imidazol-2-yl(2-pyridyl)]{2-[(5-nitro(2-pyridyl))amino]ethyl}amine.

출처 및 근거

ORD 기록
ord-ce19b0ea2ccc4c53972164da3a733e5c
출처 데이터셋
uspto-grants-2008_09
특허 번호
US07425557B2

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