2-Nitrobenzenesulfonyl chloride → {2-[(5-Nitro(2-pyridyl))amino]ethyl}[(2-nitrophenyl)sulfonyl]amine

https://huagongshe.com/reaction/31932

참여 물질

역할	이름	HCID	투입량
반응물	2-Nitrobenzenesulfonyl chloride	HCID 15540	—
반응물	Diisopropylethylamine	HCID 81531	—
반응물	2-(2-Aminoethylamino)-5-nitropyridine	HCID 122425	—
용매	Dichloromethane	HCID 6344	—
생성물	{2-[(5-Nitro(2-pyridyl))amino]ethyl}[(2-nitrophenyl)sulfonyl]amine	HCID 22142870	—

반응 조건

온도	23 °C

반응 단계

To a suspension of resin-bound (2aminoethyl)(5-nitro(2-pyridyl))amine (30 g, 21 mmol), CH2Cl2 (250 mL) and iPr2NEt (18.3 mL, 105 mmol) at 23° C. was added 2-nitrobenzenesulfonyl chloride (23.3 g, 105 mmol). The resulting mixture was shaken at 23° C. for 6 h, filtered, washed with NMP, H2O and CH2Cl2 and air dried to yield polymer-bound {2-[(5-nitro(2-pyridyl))amino]ethyl}[(2-nitrophenyl)sulfonyl]amine.

출처 및 근거

DOI	10.6084/m9.figshare.5104873.v1
특허 번호	US07425557B2
출처 데이터셋	uspto-grants-2008_09
ORD ID	ord-ae667c13acff4681a1988d929fc39f58
출처 메모	uspto-grants-2008_09