N,N'-Dimethylethylenediamine → 4-Bromotriphenylamine

HRID 31958

반응식

HRID 31958 반응식
CNCCNC.[C:7]1([NH:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1.[Br:20][C:21]1[CH:26]=[CH:25][C:24](I)=[CH:23][CH:22]=1>[Cu].C1(C)C(C)=CC=CC=1>[CH:17]1[CH:16]=[CH:15][C:14]([N:13]([C:24]2[CH:25]=[CH:26][C:21]([Br:20])=[CH:22][CH:23]=2)[C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][CH:12]=2)=[CH:19][CH:18]=1

참가 물질

6

반응물 3

HCID 8070N,N'-DimethylethylenediamineHCID 11487DiphenylamineHCID 115221-Bromo-4-iodobenzene

생성물 1

HCID 6428384-Bromotriphenylamine수율 70.2%

시약·촉매·용매 2

HCID 23978Copper촉매HCID 7237O-Xylene용매

실험 절차

N,N′-dimethylethylenediamine 1.76 g was added to diphenylamine 16.9 g, 4-bromoiodobenzene 28.2 g sodium t-butoxide 14.4 g, copper powder 3.81 g and a xylene 100 ml solution, and the mixture was heated and refluxed for 24 hours under argon atmosphere. After cooled down to room temperature, the mixture was filtered to remove an insoluble matter, and the filtrate was concentrated. The residue was refined by silica gel chromatography to obtain 22.7 g of white crystal of 4-bromotriphenylamine.

후처리

  1. temperaturerefluxed for 24 hours under argon atmosphere
  2. filtrationthe mixture was filtered
  3. customto remove an insoluble matter
  4. concentrationthe filtrate was concentrated

출처 및 근거

ORD 기록
ord-aff8d328fb5246128c3497ee689c6469
출처 데이터셋
uspto-grants-2008_09
특허 번호
US07425654B2

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