5-Aminoisoquinoline → N-Isoquinolin-5-yl-1-(5-trifluoromethylpyrid-2-yl)-piperidine-4-carboxamide

반응식

[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([N:9]2[CH2:10][CH2:11][CH:12]([C:15](=[O:16])[OH:17])[CH2:13][CH2:14]2)[n:7][cH:8]1)([F:18])[F:19].[NH2:20][c:21]1[c:22]2[cH:23][cH:24][n:25][cH:26][c:27]2[cH:28][cH:29][cH:30]1>>[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([N:9]2[CH2:10][CH2:11][CH:12]([C:15](=[O:17])[NH:20][c:21]3[c:22]4[cH:23][cH:24][n:25][cH:26][c:27]4[cH:28][cH:29][cH:30]3)[CH2:13][CH2:14]2)[n:7][cH:8]1)([F:18])[F:19]

참가 물질

반응물 2

HCID 707665-Aminoisoquinoline

HCID 27777881-[5-(Trifluoromethyl)pyridin-2-yl]piperidine-4-carboxylic acid

생성물 1

HCID 11689858N-Isoquinolin-5-yl-1-(5-trifluoromethylpyrid-2-yl)-piperidine-4-carboxamide

출처 및 근거

ORD 기록: ord-c009e3a58cae4fef99e26c2a7bff418f
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

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