(+/-)trans-1-Benzoyl-3,4-diazidopiperidine → HCID 69853211, 화합물
반응식
[C:1]([N:9]1[CH2:14][CH2:13][C@@H:12]([N:15]=[N+]=[N-])[C@H:11]([N:18]=[N+]=[N-])[CH2:10]1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>C(O)C.[Pd].CC([O-])=O.CC([O-])=O.[Pb+2]>[C:1]([N:9]1[CH2:14][CH2:13][C@@H:12]([NH2:15])[C@H:11]([NH2:18])[CH2:10]1)(=[O:8])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1참가 물질
4
실험 절차
A solution of the diazide (D26) (450 mg, 1.7 mmol) in ethanol (30 ml) was treated with Lindlar catalyst (5% Pd/CaCO3, 250 mg) and stirred under hydrogen (1 atm) for 24 hour. The mixture was filtered and solvent removed in vacuo to afford the title compound as oil, 350 mg (94%).
후처리
- filtrationThe mixture was filtered
- customsolvent removed in vacuo
출처 및 근거
- ORD 기록
- ord-446c20ba01a9409da2ada87ae8675022
- 출처 데이터셋
- uspto-grants-2001_04
- 특허 번호
- US06211107B1
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