참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | 4-(Trifluoromethyl)cinnamic acid | HCID 688070 | — |
| 촉매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 4-(Trifluoromethyl)cinnamoyl chloride | HCID 11107291 | — |
반응 단계
200.0 mg (0.92 mmol) of trans-4-trifluoromethylcinnamic acid were treated with 200 μl of thionyl chloride. After addition of 2 drops of DMF, the reaction solution obtained was stirred at 75° C. for 3 h. It was then concentrated to dryness, and the residue was taken up in toluene 2× and concentrated to dryness again. Drying in a high vacuum yielded 237.0 mg of the title compound as a slightly yellow, amorphous powder.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US06211196B1 |
|---|
| 출처 데이터셋 | uspto-grants-2001_04 |
|---|
| ORD ID | ord-fc6c1c230be84f99a7c445e3d7914d02 |
|---|
| 출처 메모 | uspto-grants-2001_04 |
|---|
