3-(4-Pyridyl)aniline → 3-[3-(4-Pyridyl)Anilino]-3-Cyclobutene-1,2-Dione

HRID 322066노트

반응식

HRID 322066 반응식
[NH2:1][C:2]1[CH:3]=[C:4]([C:8]2[CH:13]=[CH:12][N:11]=[CH:10][CH:9]=2)[CH:5]=[CH:6][CH:7]=1.C([O:18][C:19]1[C:20](=[O:24])[C:21](=O)[CH:22]=1)CCC>C(O)C>[N:11]1[CH:12]=[CH:13][C:8]([C:4]2[CH:3]=[C:2]([CH:7]=[CH:6][CH:5]=2)[NH:1][C:21]2[C:20](=[O:24])[C:19](=[O:18])[CH:22]=2)=[CH:9][CH:10]=1

참가 물질

4

반응물 2

HCID 4595233-(4-Pyridyl)anilineHCID 157231823-Butoxycyclobut-3-ene-1,2-dione

생성물 1

HCID 98378313-[3-(4-Pyridyl)Anilino]-3-Cyclobutene-1,2-Dione수율 76.8%

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

A solution of 4-(3-aminophenyl)pyridine (0.81 g) and 3-n-butoxy-3-cyclobutene-1,2-dione (0.73 g) in ethanol (20 ml) is stirred at ambient temperature for 15 hours. The resultant precipitated solid is washed with methanol and ether and recrystallized from dimethyl formamide to give 0.91 g of the title compound, mp 252-255.5° C.

후처리

  1. customThe resultant precipitated solid
  2. washis washed with methanol and ether
  3. customrecrystallized from dimethyl formamide

출처 및 근거

ORD 기록
ord-f402d218b9ee48c28e8843565ed69c3d
출처 데이터셋
uspto-grants-2001_04
특허 번호
US06211220B1

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