Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,3-Dichloroacetone → 4-[4-(Chloromethyl)-1,3-oxazol-2-yl]benzonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,3-Dichloroacetone | HCID 10793 | — |
| 반응물 | p-Cyanobenzamide | HCID 76427 | — |
| 생성물 | 4-[4-(Chloromethyl)-1,3-oxazol-2-yl]benzonitrile | HCID 22009640 | 41% |
반응 단계
In substantially the same manner as in Reference Example 31, 4-cyanobenzamide was allowed to react with 1,3-dichloroacetone to give 4-chloromethyl-2-(4-cyanophenyl)oxazole. The yield was 41%. Recrystallization form ethyl acetate-hexane gave colorless prisms, mp 134-135° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06211215B1 |
| 출처 데이터셋 | uspto-grants-2001_04 |
| ORD ID | ord-8f68c7735093494694dce59073b3aa24 |
| 출처 메모 | uspto-grants-2001_04 |